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Hitoshi Yoshiji Selected Research

CDAA (Randox)

10/2022Rifaximin and lubiprostone mitigate liver fibrosis development by repairing gut barrier function in diet-induced rat steatohepatitis.
12/2021Angiotensin Receptor Blockers Potentiate the Protective Effect of Branched-Chain Amino Acids on Skeletal Muscle Atrophy in Cirrhotic Rats.
6/2019Exogenous Administration of Low-Dose Lipopolysaccharide Potentiates Liver Fibrosis in a Choline-Deficient l-Amino-Acid-Defined Diet-Induced Murine Steatohepatitis Model.
11/2017Periostin cross‑reacts with the renin‑angiotensin system during liver fibrosis development.
10/2016DNA methylation of angiotensin II receptor gene in nonalcoholic steatohepatitis-related liver fibrosis.
3/2015Reduction of endotoxin attenuates liver fibrosis through suppression of hepatic stellate cell activation and remission of intestinal permeability in a rat non-alcoholic steatohepatitis model.
11/2013Direct renin inhibitor, aliskiren, attenuates the progression of non-alcoholic steatohepatitis in the rat model.
7/2013Dual blockade of angiotensin-II and aldosterone suppresses the progression of a non-diabetic rat model of steatohepatitis.
5/2009Losartan, an angiotensin-II type 1 receptor blocker, attenuates the liver fibrosis development of non-alcoholic steatohepatitis in the rat.
11/2008Innate immune reactivity of the liver in rats fed a choline-deficient L-amino-acid-defined diet.
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Hitoshi Yoshiji Research Topics

Disease

70Liver Cirrhosis (Hepatic Cirrhosis)
10/2022 - 07/2002
62Fibrosis (Cirrhosis)
10/2022 - 07/2002
48Hepatocellular Carcinoma (Hepatoma)
10/2022 - 04/2002
48Neoplasms (Cancer)
01/2022 - 03/2002
19Fatty Liver
10/2022 - 10/2006
15Alcoholic Fatty Liver
10/2022 - 06/2007
14Liver Diseases (Liver Disease)
05/2022 - 09/2004
13Infections
03/2022 - 05/2013
13Carcinogenesis
03/2020 - 07/2002
12Non-alcoholic Fatty Liver Disease
11/2021 - 10/2006
10Chronic Hepatitis C
10/2022 - 02/2005
10Ascites
05/2022 - 02/2017
9Hepatic Encephalopathy
03/2022 - 12/2017
9Inflammation (Inflammations)
12/2021 - 11/2009
9Insulin Resistance
08/2020 - 01/2009
8Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
03/2022 - 01/2017
7Hemorrhage
05/2022 - 11/2005
6Hyperammonemia
08/2022 - 12/2017
6Muscle Cramp (Cramp)
12/2020 - 12/2018
5Alcoholic Liver Diseases (Alcoholic Liver Disease)
12/2021 - 04/2011
5Chronic Hepatitis (Chronic Active Hepatitis)
01/2019 - 10/2004
4Liver Failure
10/2022 - 10/2011
4Sarcopenia
08/2022 - 01/2020
4Thrombosis (Thrombus)
06/2022 - 08/2017
4Thrombocytopenia (Thrombopenia)
01/2022 - 01/2006
3Pancreatic Neoplasms (Pancreatic Cancer)
05/2022 - 08/2009
3Acute-On-Chronic Liver Failure
05/2022 - 05/2020
3Thrombophilia
03/2022 - 05/2019
3Pleural Effusion (Pleural Effusions)
03/2022 - 10/2002
3Edema (Dropsy)
03/2022 - 02/2018

Drug/Important Bio-Agent (IBA)

22Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2019 - 03/2002
22Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
01/2012 - 03/2002
18InterferonsIBA
10/2022 - 02/2005
17Amino AcidsFDA Link
10/2022 - 07/2002
15Choline (Choline Chloride)IBA
10/2022 - 07/2002
15EndotoxinsIBA
05/2022 - 02/2010
14Proteins (Proteins, Gene)FDA Link
03/2022 - 10/2002
13CDAA (Randox)IBA
10/2022 - 07/2002
13CytokinesIBA
08/2022 - 05/2006
10Biomarkers (Surrogate Marker)IBA
04/2022 - 07/2003
10von Willebrand FactorIBA
04/2022 - 11/2006
10Angiogenesis Inducing Agents (Angiogenesis Factor)IBA
08/2010 - 03/2002
9Angiotensin IIIBA
12/2021 - 09/2003
9Messenger RNA (mRNA)IBA
01/2021 - 04/2002
9PerindoprilFDA LinkGeneric
11/2006 - 03/2002
8LipopolysaccharidesIBA
10/2022 - 08/2017
8Rifaximin (L 105)FDA Link
10/2022 - 12/2017
8EnzymesIBA
04/2022 - 07/2002
8Angiotensin II Type 1 Receptor BlockersIBA
01/2022 - 05/2009
8Losartan (Cozaar)FDA LinkGeneric
01/2022 - 05/2009
8Ursodeoxycholic Acid (Urso)FDA LinkGeneric
01/2022 - 02/2016
8Antiviral Agents (Antivirals)IBA
01/2022 - 01/2017
8CollagenIBA
10/2020 - 07/2002
8Pharmaceutical PreparationsIBA
12/2019 - 02/2007
7Sorafenib (BAY 43-9006)FDA Link
10/2022 - 05/2012
7Anti-Bacterial Agents (Antibiotics)IBA
12/2021 - 06/2011
7Branched-Chain Amino AcidsIBA
12/2021 - 01/2009
7Glucose (Dextrose)FDA LinkGeneric
03/2020 - 01/2006
7Glutathione Transferase (Glutathione S-Transferase)IBA
06/2018 - 07/2003
6Toll-Like Receptor 4IBA
10/2022 - 11/2008
6TolvaptanFDA Link
05/2022 - 02/2017
6AntigensIBA
04/2022 - 06/2008
6Aspartate Aminotransferases (Aspartate Transaminase)IBA
10/2021 - 09/2017
6DiureticsIBA
01/2021 - 02/2017
6Therapeutic UsesIBA
12/2020 - 01/2003
6Tissue Inhibitor of Metalloproteinase-1IBA
11/2006 - 10/2002
5Serum AlbuminIBA
04/2022 - 01/2018
5Angiotensin Receptor AntagonistsIBA
12/2021 - 07/2011
5Transforming Growth Factor beta (TGF-beta)IBA
12/2016 - 05/2006
5Vitamin KFDA Link
05/2011 - 01/2007
4BilirubinIBA
05/2022 - 05/2012
4Carbon Tetrachloride (Tetrachloromethane)IBA
12/2021 - 01/2017
4Carrier Proteins (Binding Protein)IBA
10/2021 - 09/2017
4RNA (Ribonucleic Acid)IBA
07/2021 - 08/2005
4Interleukin-8 (Interleukin 8)IBA
06/2021 - 07/2005
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2021 - 11/2008
4Prednisolone (Predate)FDA LinkGeneric
01/2021 - 01/2018
4Alanine Transaminase (SGPT)IBA
04/2020 - 11/2006
4Insulin (Novolin)FDA Link
04/2020 - 01/2006
4Ribavirin (Virazole)FDA LinkGeneric
01/2019 - 01/2006
4Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
09/2017 - 03/2002
4AldosteroneIBA
08/2017 - 05/2010
4Vitamin K 2 (Vitamin K2)IBA
08/2009 - 03/2005
4Imatinib Mesylate (Gleevec)FDA Link
04/2009 - 05/2005
4Cyclin D1IBA
05/2005 - 03/2003
3SteroidsIBA
03/2022 - 05/2012
3AmmoniaIBA
03/2022 - 12/2018
3ZincIBA
03/2022 - 06/2021
3lusutrombopagIBA
01/2022 - 01/2020
3alpha-Fetoproteins (alpha-Fetoprotein)IBA
01/2022 - 06/2007
3DNA (Deoxyribonucleic Acid)IBA
01/2022 - 05/2006
3Bile Acids and Salts (Bile Acids)IBA
01/2022 - 11/2017
3lenvatinibIBA
01/2022 - 01/2021
3Vasopressins (Vasopressin)IBA
12/2021 - 11/2005
3AlbuminsIBA
10/2021 - 01/2017
3Hyaluronic Acid (Hyaluronan)IBA
10/2021 - 08/2020

Therapy/Procedure

43Therapeutics
05/2022 - 03/2002
10Drug Therapy (Chemotherapy)
01/2022 - 12/2014
8Oral Administration
10/2022 - 05/2005
6Chemoprevention
10/2014 - 11/2004